NR-507 Advanced Pathophysiology
NR507 Midterm Exam
Hypersensitivity: Type 1
Correct Answer:
-Mediated IgE -inflammation due to mast cell degranultion -anaphylactic, asthma, hay fever
treatment: epinephrine
Hypersensitivity: Type 2
Correct Answer:
-Cytotoxic reaction: tissue specific
-binds to the antigen ON THE CELL SURFACE -macrophages are primary effectors cells involved cause tissue damage or alter function
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Hypersensitivity 2
Correct Answer:
-Graves Disease (hyperthyroidism) -alters function not destroy -blood transfusions reaction- transfused erythrocytes are destroyed by agglutination or lysis -drug allergies -hemolytic anemia
Hypersensitivity: type 3
Correct Answer:
-Not organ specific -antibody binds to soluble antigen OUTSIDE THE CELL SURFACE that was released into the blood or bodily fluids, and the complex is then deposited in the tissues
Hypersensitivity: Type 3
Correct Answer:
-rheumatoid arthritis -Systemic Lupus Erythematosus (SLE) -Raynaud's
Hives (urticaria)
Correct Answer:
Hypersensitivity Type 1
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First responders to innate the immune system
Correct Answer:
Neutrophils
Allergic contact dermatitis
Correct Answer:
Hypersensitivity Type IV
Type 2 cytotoxic hypersensitivity mediated by:
Correct Answer:
-IgG IgM -macrophages are primary effort cells
Serum Sickness
Correct Answer:
type 3 hypersensitivity
Hypersensitivity IV,
Correct Answer:
-is more of a delayed immune response.-mediated T-cells attack tissue directly (no antibodies)
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Autoimmune
Correct Answer:
-diseases in which the body makes antibodies directed against its own tissues
Primary immunodeficiency
Correct Answer:
-Genetic; inherited -result of single gene defects -B and T cell deficiencies
secondary immunodeficiency
Correct Answer:
-acquired
Common cause of secondary immunodeficiency
Correct Answer:
Malnutrition
Most patients diagnosed with SLE will have a positive ?
Correct Answer:
antinuclear antibody (ANA)
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